I've got pihole running on a Raspberry PI. I've set it up to respond to 2 IP addresses. This was the command to add the 2nd IP.
sudo nmcli connection modify "Wired connection 1" +ipv4.addresses 192.168.1.3/24 sudo nmcli connection up "Wired connection 1"
It just means that for devices that require 2 DNS servers I can specify both to force it to always use (the same) pihole instance.
Source: r/pihole · by /u/flammable_donut